Search results for "L-ascorbic acid"

showing 3 items of 3 documents

Influence of storage and in vitro gastrointestinal digestion on totqal antioxidant capacity of fruit beverages

2011

Eight fruit beverages containing grape, orange and apricot, with/without iron and/or zinc and with/without milk added were analyzed for total antioxidant capacity (ORAC and TEAC methods), ascorbic acid content, and total polyphenols. The influence of cold storage (2-4 degrees C) during the product shelf-life (135 days) and antioxidant capacity after an in vitro gastrointestinal digestion were evaluated. Antioxidant capacity for all beverages together increased significantly (p < 0.05) at the end of storage (16.4% and 12.8% for ORAC and TEAC, respectively), whereas ascorbic acid remained stable. Regarding in vitro digestion, antioxidant values of bioaccessible fractions of fruit beverages in…

VitaminTotal polyphenolsAntioxidantmedicine.medical_treatmentESTADISTICA E INVESTIGACION OPERATIVATotal antioxidant capacityCold storageFruit beveragesStorageIn vitro gastrointestinal digestionBioaccessibilityOrange (colour)L-Ascorbic acidchemistry.chemical_compoundmedicineFood scienceFood analysisFood preservationfood and beveragesFood composition dataAscorbic acidchemistryPolyphenolFood compositionFood Science
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Spray-Drying Performance and Thermal Stability of L-Ascorbic Acid Microencapsulated with Sodium Alginate and Gum Arabic

2019

[EN] The potential of sodium alginate (ALG) and gum arabic (GA) as wall polymers for Lascorbic acid (AA) encapsulation as a tool for their preservation against the thermo-oxidative degradation was investigated. The influence of such polymers used as wall material on the AAcontent, size, encapsulation efficiency, encapsulation yield and thermo-oxidative stability were evaluated. The AA-microparticles were obtained using the spray-drying technique. An experimental Taguchi design was employed to assess the influence of the variables in the encapsulation process. The microparticles morphology and size distribution were characterized by scanning electron microscopy and laser diffraction. The the…

0106 biological sciencesfood.ingredientMaterials scienceChemical PhenomenaScanning electron microscopeAlginatesDrug Compoundinggum arabicPharmaceutical ScienceAscorbic AcidL-ascorbic acid01 natural sciencesArticleAnalytical Chemistrysodium alginatelcsh:QD241-4410404 agricultural biotechnologyfoodDifferential scanning calorimetryDrug Stabilitylcsh:Organic chemistry010608 biotechnologyDrug DiscoveryThermal stabilityspray-dryingPhysical and Theoretical ChemistryParticle Sizechemistry.chemical_classificationAnalysis of VarianceMolecular StructurenanotechnologySpectrum AnalysisOrganic ChemistryTemperature04 agricultural and veterinary sciencesPolymerAscorbic acid040401 food scienceThermogravimetrychemistryChemical engineeringChemistry (miscellaneous)Spray dryingMAQUINAS Y MOTORES TERMICOSMolecular MedicineGum arabicencapsulation
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The new 5- or 6-azapyrimidine and cyanuric acid derivatives of L-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic space…

2011

Abstract We report on the synthesis of the novel types of cytosine and 5-azacytosine (1–9), uracil and 6-azauracil (13–18) and cyanuric acid (19–22) derivatives of l -ascorbic acid, and on their cytostatic activity evaluation in human malignant tumour cell lines vs. their cytotoxic effects on human normal fibroblasts (WI38). The CD spectra analysis revealed that cytosine (5 and 6), uracil (14–16), 6-azauracil (17) and cyanuric acid (21) derivatives of l -ascorbic acid bearing free amino group at ethylenic spacer existed as a racemic mixture of enantiomers, whereas L-ascorbic derivatives containing the C-5 substituted hydroxy group at the ethylenic spacer were obtained in (4R, 5S) enantiomer…

Double bondStereochemistryAscorbic AcidCrystallography X-Ray010402 general chemistry01 natural sciencesCell LineCytosineInhibitory Concentration 50Structure-Activity Relationship03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDrug DiscoveryHumansUracilta116Pharmacologychemistry.chemical_classificationTriazinespyrimidine and cyanuric acid derivatives; L-ascorbic acid; circular dichroism; cytostatic activity evaluation; X-ray diffractionOrganic ChemistryAbsolute configurationHydrogen BondingStereoisomerismUracilBiological activityHep G2 CellsGeneral MedicineFibroblastsCytostatic AgentsAscorbic acidpyrimidine and cyanuric acid derivatives ; L-ascorbic acid ; circular dichroism ; cytostatic activity evaluation ; X-ray diffraction ; cell cycle analysis0104 chemical sciences3. Good healthchemistry030220 oncology & carcinogenesisS Phase Cell Cycle CheckpointsMCF-7 CellsCyanuric acidCytosineLactoneHeLa Cells
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